Special agents Angus MacGyver and Jack Dalton join forces to recover a missing bio-weapon, with the ability to destroy hundreds of thousands of people with one single drop.

MacGyver and the team attempt to rescue Sarah, Jack's former CIA partner, who went missing in Venezuela after obtaining evidence to take down an international arms dealer.

The team has to figure out a way to pick up a terror sponsor from Labuan, Malaysia, and get info from him on D77's next terror attack.

Ex Spetsnaz Colonel Chevchenko and his men have stolen a 10MT nuclear bomb. The team needs the help from a Russian defector in a Virginia retirement home to shut it down. Where's the bomb?

Using only an armrest, a curtain rod and a toothpick, MacGyver must fix a sabotaged train in order to protect a whistleblower who has proof that her boss is selling weapons to U.S. enemies.

Using only a wrench and rope, MacGyver must diffuse a bomb set near the United Nations by his old nemesis, "The Ghost", a notorious criminal whose work killed his mentor, and track him down before he strikes again.

MacGyver is tasked to go undercover as an inmate in a maximum security prison to break out El Noche, a notorious drug kingpin, using only batteries and salt, and track him to his cartel's secret location and dismantle it.

MacGyver comes face to face with Murdoc, an international assassin hired to kill him, he must defend both himself and Bozer, armed with only a corkscrew and paper towel rolls.

With only a chisel and matchbook, MacGyver and team must defend U. S. embassy workers in Latvia from extremists attempting to retrieve their leader.

MacGyver uses pliers to rescue the kidnapped prodigy from his old middle school.

Using a microwave and a power strip, MacGyver and Jack look for Riley when she disappears after hacking into the NSA, possibly starting World War III.

Mac and Jack are on a mission with their exes to catch a high level mole. Davis and Bozer support from afar and gather vital info.

Matty gets the promotion, Jack'd hoped for. After catching a war criminal in Kazakhstan, Mac and Jack's chopper's shot down. Can they catch the war criminal again and get away?

Using a fish scaler and fishing wire, Mac and Jack must track down a corrupt FBI agent, who has framed a man for murder.

Sin Resumen

The Matty/Jack past comes up repeatedly. Mac and Jack try to catch a fugitive, when they're repeatedly outsmarted by a bounty hunter family. Can Davis and Bozer do better?

On a surveillance mission in Amsterdam, their target, a Dutch MP, gets a ticking bomb from terrorists. Mac takes it away. They end as terrorist suspects hunted by the police.

Mac and the team travel to Hawaii to help out when an earthquake strikes and partner with Chin Ho and Kono to rescue a group of government scientists trapped in a building about to collapse.

Mac and Jack help Mac's close friend from M.I.T. after she fakes her own death to prevent someone from killing her in order to suppress her scientific research.

The team intercepts a message for Murdoc from a terror group, so Mac poses as Murdoc to protect their intended target.

Murdoc enacts his plan to kill every agent in the Phoenix Complex.